Patterns, Gradients and Signals in Soft Biomaterials
The interdisciplinary
research group on Patterns, Gradients and Signals in
Soft Biomaterials seeks to  develop macromolecular materials with predictable
biological response by combining understanding of macromolecular synthesis,
experimental and theoretical nanomechanics, and cell biology to move
towards a comprehensive understanding of biological structure-function
relationships in soft materials. Artificial extracellular matrix
(aECM) proteins which enable novel functions are being developed as
artificial substrates for cell-surface interactions. Cell migration
and assembly are investigated using these substrates,
and the mechanical properties of cells and their bioactive
substrates are studied experimentally and theoretically.
This IRG builds on the work of the previous IRG on Biological
Synthesis & Assembly
of Macromolecular Materials.
Faculty
Anand
Asthagiri
Julia
Kornfield
Rob
Phillips
G. Ravichandran
David
Tirrell (Team Leader)
Zhen-Gang Wang
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